Article
Influence of aquaporin-1 gene polymorphism on water retention in liver cirrhosis.
Scandinavian journal of gastroenterology - 1 Oct 2011
Fábrega Emilio, Berja Ana, García-Unzueta María Teresa, Guerra-Ruiz Armando, Cobo Marta, López María, Bolado-Carrancio Alfonso, Amado José Antonio, Rodríguez-Rey José Carlos, Pons-Romero Fernando
Abstract excerpt
UNLABELLED: Water retention is a major clinical problem in patients with liver cirrhosis. The factors that predispose to water retention are poorly understood but may involve genetic factors. Recent research suggests that renal aquaporins may be a pathophysiological factor involved in this condition. Aquaporin-1 (AQP1) is expressed in the proximal tubule and aquaporin-2 (AQP2) in the renal collecting duct cells....
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