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Article

The role of epithelial cell adhesion molecule N-glycosylation on apoptosis in breast cancer cells.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Mar 2017

Zhang Dandan, Liu Xue, Gao Jiujiao, Sun Yan, Liu Tingjiao, Yan Qiu, Yang Xuesong

Abstract excerpt

Glycosylation of cell surface proteins plays an important role in the regulation of apoptosis. It has been demonstrated that knockdown of epithelial cell adhesion molecule promoted apoptosis, inhibited cell proliferation, and caused cell-cycle arrest. In this study, we investigated whether and how N-glycosylation of epithelial cell adhesion molecule influenced the apoptosis in breast cancer cells. We applied the...

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PMID: 28349835
DOI: 10.1177/1010428317695973

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