Article
Immune Recognition of the Epidemic Cystic Fibrosis Pathogen Burkholderia dolosa.
Infection and immunity - 1 Jun 2017
Roux Damien, Weatherholt Molly, Clark Bradley, Gadjeva Mihaela, Renaud Diane, Scott David, Skurnik David, Priebe Gregory P, Pier Gerald, Gerard Craig, Yoder-Himes Deborah R
Abstract excerpt
Burkholderia dolosa caused an outbreak in the cystic fibrosis (CF) clinic at Boston Children's Hospital from 1998 to 2005 and led to the infection of over 40 patients, many of whom died due to complications from infection by this organism. To assess whether B. dolosa significantly contributes to disease or is recognized by the host immune response, mice were infected with a sequenced outbreak B. dolosa strain,...
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