Article
Phosphorylation of the F-BAR protein Hof1 drives septin ring splitting in budding yeast.
Nature communications - 22 Apr 2024
Varela Salgado Maritzaida, Adriaans Ingrid E, Touati Sandra A, Ibanes Sandy, Lai-Kee-Him Joséphine, Ancelin Aurélie, Cipelletti Luca, Picas Laura, Piatti Simonetta
Abstract excerpt
A double septin ring accompanies cytokinesis in yeasts and mammalian cells. In budding yeast, reorganisation of the septin collar at the bud neck into a dynamic double ring is essential for actomyosin ring constriction and cytokinesis. Septin reorganisation requires the Mitotic Exit Network (MEN), a kinase cascade essential for cytokinesis. However, the effectors of MEN in this process are unknown. Here we...
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