Article
Phosphorylation of Pnut in the Early Stages of Drosophila Embryo Development Affects Association of the Septin Complex with the Membrane and Is Important for Viability.
G3 (Bethesda, Md.) - 4 Jan 2018
Akhmetova Katarina, Balasov Maxim, Svitin Anton, Chesnokova Elena, Renfrow Matthew, Chesnokov Igor
Abstract excerpt
Septin proteins are polymerizing GTPases that are found in most eukaryotic species. Septins are important for cytokinesis and participate in many processes involving spatial modifications of the cell cortex. In Drosophila, septin proteins Pnut, Sep1, and Sep2 form a hexameric septin complex. Here, we found that septin protein Pnut is phosphorylated during the first 2 hr of Drosophila embryo development. To study...
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