Article
Critical roles of CTP synthase N-terminal in cytoophidium assembly.
Experimental cell research - 15 May 2017
Huang Yong, Wang Jin-Jun, Ghosh Sanjay, Liu Ji-Long
Abstract excerpt
Several metabolic enzymes assemble into distinct intracellular structures in prokaryotes and eukaryotes suggesting an important functional role in cell physiology. The CTP-generating enzyme CTP synthase forms long filamentous structures termed cytoophidia in bacteria, yeast, fruit flies and human cells independent of its catalytic activity. However, the amino acid determinants for protein-protein interaction...
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