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Article

The Interplay between Myc and CTP Synthase in Drosophila.

PLoS genetics - 1 Feb 2016

Aughey Gabriel N, Grice Stuart J, Liu Ji-Long

Abstract excerpt

CTP synthase (CTPsyn) is essential for the biosynthesis of pyrimidine nucleotides. It has been shown that CTPsyn is incorporated into a novel cytoplasmic structure which has been termed the cytoophidium. Here, we report that Myc regulates cytoophidium formation during Drosophila oogenesis. We have found that Myc protein levels correlate with cytoophidium abundance in follicle epithelia. Reducing Myc levels...

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Identifiers

PMID: 26889675
DOI: 10.1371/journal.pgen.1005867
PMCID: PMC4759343

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The Interplay between Myc and CTP Synthase in Drosophila.PMID 26889675Read ↗

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Critical roles of CTP synthase N-terminal in cytoophidium assembly.Semantic proximity Read ↗

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Max-independent functions of Myc in Drosophila melanogaster.Semantic proximity Read ↗

CTP synthase polymerization in germline cells of the developing Drosophila egg supports egg production.Semantic proximity Read ↗

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