Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of a molecular signaling gene-gene regulatory network between GWAS susceptibility genes ADTRP and MIA3/TANGO1 for coronary artery disease.

Biochimica et biophysica acta. Molecular basis of disease - 1 Jun 2017

Luo Chunyan, Wang Fan, Ren Xiang, Ke Tie, Xu Chengqi, Tang Bo, Qin Subo, Yao Yufeng, Chen Qiuyun, Wang Qing Kenneth

Abstract excerpt

Coronary artery disease (CAD) is the leading cause of death worldwide. GWAS have identified >50 genomic loci for CAD, including ADTRP and MIA3/TANGO1. However, it is important to determine whether the GWAS genes form a molecular network. In this study, we have uncovered a novel molecular network between ADTRP and MIA3/TANGO1 for the pathogenesis of CAD. We showed that knockdown of ADTRP expression markedly...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aryl Hydrocarbon Receptor Nuclear Translocator
Share to Atherosclerosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Coronary Artery Disease

Share to Gene Expression Regulation

Share to Gene Regulatory Networks

Share to Hep G2 Cells

Share to Human Umbilical Vein Endothelial Cells

Share to Phosphatidylinositol 3-Kinases

Source

Open in PubMed Open full text

Identifiers

PMID: 28341552
DOI: 10.1016/j.bbadis.2017.03.010
PMCID: PMC5616168

Genes

MIA3
ADTRP
CAD
AKT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of a molecular signaling gene-gene regulatory network between GWAS susceptibility genes ADTRP and MIA3/TANGO1 for coronary artery disease.PMID 28341552Read ↗

Statistical and Functional Studies Identify Epistasis of Cardiovascular Risk Genomic Variants From Genome-Wide Association Studies.Semantic proximity Read ↗

Identification of Risk Pathways and Functional Modules for Coronary Artery Disease Based on Genome-wide SNP Data.Semantic proximity Read ↗

GATA2 regulates the CAD susceptibility gene ADTRP rs6903956 through preferential interaction with the G allele.Semantic proximity Read ↗

Integrative genomics reveals novel molecular pathways and gene networks for coronary artery disease.Semantic proximity Read ↗

Transcriptome wide association study of coronary artery disease identifies novel susceptibility genesSemantic proximity Read ↗

Network-Based Identification and Prioritization of Key Regulators of Coronary Artery Disease Loci.Semantic proximity Read ↗

Identification of susceptibility modules for coronary artery disease using a genome wide integrated network analysis.Semantic proximity Read ↗

Transcriptome-wide association study of coronary artery disease identifies novel susceptibility genes.Semantic proximity Read ↗

Shared Biological Pathways Between Alzheimer’s Disease and Ischemic StrokeSemantic proximity Read ↗

A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese.Semantic proximity Read ↗

Transcriptome wide association study of coronary artery disease identifies novel susceptibility genesSemantic proximity Read ↗

Molecular genetics of coronary artery disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.