Article
GATA2 regulates the CAD susceptibility gene ADTRP rs6903956 through preferential interaction with the G allele.
Molecular genetics and genomics : MGG - 1 Jul 2021
Luo Chunyan, Tang Bo, Qin Subo, Yuan Chengfu, Du Youqin, Yang Jian
Abstract excerpt
Myocardial infarction (MI) is a frequent outcome of coronary artery disease (CAD) and the key factor contributing to worldwide disability and death. Genetic factors contribute to the pathogenesis of CAD/MI, and SNP rs6903956 in the ADTRP gene was first found associated with CAD/MI in the Chinese Han population, which was successfully replicated in other cohorts. However, whether rs6903956 is a functional SNP and...
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