Article
Next-generation sequencing of urine specimens: A novel platform for genomic analysis in patients with non-muscle-invasive urothelial carcinoma treated with bacille Calmette-Guérin.
Cancer cytopathology - 1 Jun 2017
Scott Sasinya N, Ostrovnaya Irina, Lin Caroline M, Bouvier Nancy, Bochner Bernard H, Iyer Gopakumar, Solit David, Berger Michael F, Lin Oscar
Abstract excerpt
BACKGROUND: Biopsies from patients with high-risk (HR) non-muscle-invasive urothelial carcinoma (NMIUC), especially flat urothelial carcinoma in situ, frequently contain scant diagnostic material or denuded mucosa only, and this precludes further extensive genomic analysis. This study evaluated the use of next-generation sequencing (NGS) analysis of urine cytology material from patients with HR NMIUC in an...
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