Article

Clinical Utility of Urine DNA for Noninvasive Detection and Minimal Residual Disease Monitoring in Urothelial Carcinoma

2022-04-22

Abstract excerpt

Current methods for the early detection and minimal residual disease (MRD) monitoring of urothelial carcinoma (UC) are invasive and/or possess suboptimal sensitivity. We developed an efficient workflow named urine tumor DNA multidimensional bioinformatic predictor (utLIFE). Using UC-specific mutations and large copy number variations, utLIFE-UC model was developed on bladder cancer cohort (n = 150) and validated i...

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Literature Corpus work: ae276c48-0e20-5bf7-9511-54d2f0475178
DOI: 10.21203/rs.3.rs-1557646/v1

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