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Article

Protective BCL11A and HBS1L-MYB polymorphisms in a cohort of 102 Congolese patients suffering from sickle cell anemia.

Journal of clinical laboratory analysis - 1 Jan 2018

Mikobi Tite Minga, Tshilobo Lukusa Prosper, Aloni Michel Ntetani, Lumaka Aimé Zola, Kaba Didine Kinkodi, Devriendt Koenraad, Matthijs Gert, Mbuyi Muamba Jean Marie, Race Valérie

Abstract excerpt

BACKGROUND: We aimed to investigate the distribution of selected BCL11A and HMIP polymorphisms (SNP's), and to assess the correlation with HPFH in a cohort of sickle cell patients. METHODS: A preliminary cross-sectional study was conducted in 102 patients. Group 1 was composed of patients with HPFH and Group 2 consisted of patients without HbF. We assessed 8 SNPs previously associated with HPFH in cohorts...

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Share to Anemia, Sickle Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Fetal Hemoglobin

Share to GTP-Binding Proteins

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Source

Open in PubMed Open full text

Identifiers

PMID: 28332727
DOI: 10.1002/jcla.22207
PMCID: PMC6817165

Genes

MYB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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