Article
Polymorphisms of chromogranin B gene associated with schizophrenia in Chinese Han population.
Neuroscience letters - 3 May 2002
Zhang Bifeng, Tan Zheng, Zhang Changshun, Shi Yongyong, Lin Zhixin, Gu Niufan, Feng Guoyin, He Lin
Abstract excerpt
Chromogranin is a widespread family of proteins in the neurosystem, whose function is guiding the sorting and secretion of neuropeptides. Using functional and positional evidences, chromogranin B was selected as a candidate gene for schizophrenia. We systematically screened all the promoter and exon regions of the gene and detected 15 single nucleotide polymorphisms (SNPs), among which four SNPs (including two...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.