Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IGFBP3 Modulates Lung Tumorigenesis and Cell Growth through IGF1 Signaling

22 Mar 2017

Abstract excerpt

Abstract Insulin-like growth factor binding protein 3 (IGFBP3) modulates cell growth through IGF-dependent and -independent mechanisms. Reports suggest that the serum levels of IGFBP3 are associated with various cancers and that IGFBP3 expression is significantly decreased in cisplatin (CDDP)-resistant lung cancer cells. Based on these findings, we investigated whether Igfbp3 deficiency accelerates mouse lung...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Hypoxia, and Metabolism
Share to Growth Hormone and Insulin-like Growth Factors
Share to Metabolism, Diabetes, and Cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28330997
DOI: 10.1158/1541-7786.mcr-16-0390

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IGFBP3 Modulates Lung Tumorigenesis and Cell Growth through IGF1 SignalingPMID 28330997Read ↗

Systematic analysis of IGF2BP family members in non-small-cell lung cancer.Semantic proximity Read ↗

Increased expression of Id1 and Id3 promotes tumorigenicity by enhancing angiogenesis and suppressing apoptosis in small cell lung cancerSemantic proximity Read ↗

Different Roles of the Insulin-like Growth Factor (IGF) Axis in Non-small Cell Lung CancerSemantic proximity Read ↗

Effects of upregulation of Id3 in human lung adenocarcinoma cells on proliferation, apoptosis, mobility and tumorigenicitySemantic proximity Read ↗

IGFBP-3 is a metastasis suppression gene in prostate cancer.Semantic proximity Read ↗

Single nucleotide polymorphisms of IGFBP-3 gene and lung cancer risk in a Korean population.Semantic proximity Read ↗

Gene expression and prognosis of insulin‑like growth factor‑binding protein family members in non‑small cell lung cancerSemantic proximity Read ↗

Targeting 14-3-3ζ overcomes resistance to EGFR-TKI in lung adenocarcinoma via BMP2/Smad/ID-1 signalingSemantic proximity Read ↗

IGFBP-3 regulates esophageal tumor growth through IGF-dependent and independent mechanisms.Semantic proximity Read ↗

IGFBP-3: A cell fate pivot in cancer and diseaseSemantic proximity Read ↗

ERBB3-independent activation of the PI3K pathway in EGFR-mutant lung adenocarcinomas.Semantic proximity Read ↗

A 3'-untranslated region polymorphism in IGF1 predicts survival of non-small cell lung cancer in a Chinese population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.