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Different Roles of the Insulin-like Growth Factor (IGF) Axis in Non-small Cell Lung Cancer

9 Jun 2022

Abstract excerpt

Non-small cell lung cancer (NSCLC) remains one of the deadliest malignant diseases, with high incidence and mortality worldwide. The insulin-like growth factor (IGF) axis, consisting of IGF-1, IGF-2, related receptors (IGF-1R, -2R), and high-affinity binding proteins (IGFBP 1-6), is associated with promoting fetal development, tissue growth, and metabolism. Emerging studies have also identified the role of the...

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Cancer-related molecular mechanisms research
Growth Hormone and Insulin-like Growth Factors
RNA modifications and cancer

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36062855
DOI: 10.2174/1381612828666220608122934

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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