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Article

Association of Mutations in Toll-like Receptor 2 Signaling Genes With Fulminant Form of Hepatitis B-Related Acute Liver Failure.

The Journal of infectious diseases - 15 Apr 2017

Han Yue, Gu Leilei, Liu Jing, Li Xinhua, Wang Mingjie, Gong Qiming, Yu Demin, Yang Zhitao, Zhang Donghua, Yang Huijuan, Shen Zhongliang, Zhu Hongguang, Xie Youhua, Zhang Xinxin

Abstract excerpt

Background: The fulminant form of hepatitis B-related acute liver failure (FHB-ALF) is a rare but highly fatal outcome of acute hepatitis B virus (HBV) infection. Its related host factors have not been studied to our knowledge. Methods: To identify functionally relevant biological pathway(8) in FHB-ALF pathogenesis, pathway enrichment analysis was conducted on a data set of rare case-specific variants derived...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28329297
DOI: 10.1093/infdis/jix097

Genes

TLR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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