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Article

Virus-related liver cirrhosis: molecular basis and therapeutic options.

World journal of gastroenterology - 7 Jun 2014

Lin Ji, Wu Jian-Feng, Zhang Qi, Zhang Hong-Wei, Cao Guang-Wen

Abstract excerpt

Chronic infections with hepatitis B virus (HBV) and/or hepatitis C virus (HCV) are the major causes of cirrhosis globally. It takes 10-20 years to progress from viral hepatitis to cirrhosis. Intermediately active hepatic inflammation caused by the infections contributes to the inflammation-necrosis-regeneration process, ultimately cirrhosis. CD8(+) T cells and NK cells cause liver damage via targeting the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24914367
DOI: 10.3748/wjg.v20.i21.6457
PMCID: PMC4047331

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