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TOX and ADIPOQ Gene Polymorphisms Are Associated with Antipsychotic-Induced Weight Gain in Han Chinese.

Scientific reports - 22 Mar 2017

Li Shen, Xu Chengai, Tian Yuan, Wang Xueshi, Jiang Rui, Zhang Miaomiao, Wang Lili, Yang Guifu, Gao Ying, Song Chenyu, He Yukun, Zhang Ying, Li Jie, Li Wei-Dong

Abstract excerpt

To find the genetic markers related to the antipsychotic-induced weight gain (AIWG), we analyzed associations among candidate gene single-nucleotide polymorphisms (SNPs) and quantitative traits of weight changes and lipid profiles in a Chinese Han population. A total of 339 schizophrenic patients, including 86 first-episode patients (FEPs), meeting the entry criteria were collected. All patients received atypical...

Topics

Adiponectin
Adult
Antipsychotic Agents
Brain-Derived Neurotrophic Factor
China
Female
High Mobility Group Proteins
Humans
Male
Middle Aged
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Schizophrenia

Waist-Hip Ratio

Weight Gain

Source

Open in PubMed Open full text

Identifiers

PMID: 28327672
DOI: 10.1038/srep45203
PMCID: PMC5361121

Genes

ADIPOQ
TOX
BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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