Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mesenchymal stem cells attenuate adriamycin-induced nephropathy by diminishing oxidative stress and inflammation via downregulation of the NF-kB.

Nephrology (Carlton, Vic.) - 1 May 2018

Song In-Hwan, Jung Kyong-Jin, Lee Tae-Jin, Kim Joo-Young, Sung Eon-Gi, Bae Young Chul, Park Yong Hoon

Abstract excerpt

AIM: This study aimed to evaluate the molecular mechanism mitigating progress of chronic nephropathy by mesenchymal stem cells (MSCs). METHODS: Rats were divided into normal control (Normal), adriamycin (ADR)+vehicle (CON), and ADR+MSC (MSC) groups. Nephropathy was induced by ADR (4 mg/kg) and MSCs (2 × 106 ) were injected. Rats were euthanized 1 or 6 weeks after ADR injection. NF-kB, MAPKs, inflammation,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Coculture Techniques
Share to Doxorubicin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fibrosis

Share to Glomerulosclerosis, Focal Segmental

Share to Inflammation Mediators

Share to Mesenchymal Stem Cell Transplantation

Share to Mesenchymal Stem Cells

Share to NF-kappa B

Source

Identifiers

PMID: 28326639
DOI: 10.1111/nep.13047

Genes

MSC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mesenchymal stem cells attenuate adriamycin-induced nephropathy by diminishing oxidative stress and inflammation via downregulation of the NF-kB.PMID 28326639Read ↗

Mesenchymal Stem Cells Ameliorate Interstitial Fibrosis in Adenine-induced Nephropathy Based on Renal ProteomicsSemantic proximity Read ↗

Network pharmacology and experimental validation of andrographolide’s renoprotective effects on diabetic nephropathy via AGEs-RAGE signaling and mitophagy pathwaysSemantic proximity Read ↗

Apamin inhibits renal interstitial inflammation and fibrosis via suppressing TGF-β1 and STAT3 signaling pathway in vivo and in vitroSemantic proximity Read ↗

Medicinal Plants and Phytochemicals used in Diabetic Nephropathy: A Comprehensive ReviewSemantic proximity Read ↗

Bergapten Ameliorates Renal Fibrosis by Inhibiting FerroptosisSemantic proximity Read ↗

DsbA-L mediated renal tubulointerstitial fibrosis in UUO mice.Semantic proximity Read ↗

Differentiation of Mesenchymal Stem Cells Towards Nephrogenic Lineage and Their Enhanced Resistance to Oxygen Peroxide-induced Oxidative Stress.Semantic proximity Read ↗

Nephropathic Cystinosis: Pathogenic Roles of Inflammation and Potential for New TherapiesSemantic proximity Read ↗

Enhanced Renoprotective Effect of GDNF-Modified Adipose Derived Mesenchymal Stem Cells on Renal Interstitial FibrosisSemantic proximity Read ↗

Inducible ATF3–NFAT axis aggravates podocyte injurySemantic proximity Read ↗

Inhibition of PKC-δ retards kidney fibrosis via inhibiting cGAS-STING signaling pathway in miceSemantic proximity Read ↗

Role of the TGF‑β/Smad signaling pathway in the transition from acute kidney injury to chronic kidney disease (Review)Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.