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Article

FOXL2 Mutation Status in Granulosa Theca Cell Tumors of the Ovary.

International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists - 1 Nov 2017

Nolan Amber, Joseph Nancy M, Sangoi Ankur R, Rabban Joseph, Zaloudek Charles, Garg Karuna

Abstract excerpt

Ovarian sex-cord stromal tumors that have between 10% and 50% granulosa cells in a prominent fibrothecomatous background have been referred to as granulosa theca cell tumors or mixed granulosa theca cell tumors. The classification and prognosis of these tumors is not clear. Most adult granulosa cell tumors of the ovary harbor a mutation in the FOXL2 gene, whereas fibromas and thecomas lack this mutation. The aim...

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Source

Identifiers

PMID: 28319575
DOI: 10.1097/PGP.0000000000000377

Genes

FOXL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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FOXL2 Mutation Status in Granulosa Theca Cell Tumors of the Ovary.PMID 28319575Read ↗

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Impact of FOXL2 mutations on signaling in ovarian granulosa cell tumors.Semantic proximity Read ↗

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Molecularly Defined Adult Granulosa Cell Tumor of the Ovary: The Clinical Phenotype.Semantic proximity Read ↗

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