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Article

Ovarian cellular fibromas lack FOXL2 mutations: a useful diagnostic adjunct in the distinction from diffuse adult granulosa cell tumor.

The American journal of surgical pathology - 1 Sept 2013

McCluggage W Glenn, Singh Naveena, Kommoss Stefan, Huntsman David G, Gilks C Blake

Abstract excerpt

Ovarian cellular fibromas are uncommon neoplasms, which may result in considerable diagnostic confusion with diffuse adult granulosa cell tumor. This is an important distinction, as the former usually exhibits benign behavior, whereas the latter is a low-grade malignant neoplasm capable of recurrence and metastasis. FOXL2 mutation (402C→G) has been demonstrated in >95% of ovarian adult granulosa cell tumors, only...

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Source

Identifiers

PMID: 23774170
DOI: 10.1097/PAS.0b013e31828e4f55

Genes

FOXL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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