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Article

A BEST example of channel structure annotation by molecular simulation.

Channels (Austin, Tex.) - 4 Jul 2017

Rao Shanlin, Klesse Gianni, Stansfeld Phillip J, Tucker Stephen J, Sansom Mark S P

Abstract excerpt

An increasing number of ion channel structures are being determined. This generates a need for computational tools to enable functional annotation of channel structures. However, several studies of ion channel and model pores have indicated that the physical dimensions of a pore are not always a reliable indicator of its conductive status. This is due to the unusual behavior of water within nano-confined spaces,...

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Identifiers

PMID: 28319451
DOI: 10.1080/19336950.2017.1306163
PMCID: PMC5555266

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BEST1

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