Mass spectrometric identification of SUMO substrates provides insights into heat stress-induced SUMOylation in plants

Abstract excerpt

The covalent addition of Small Ubiquitin-Related Modifier (SUMO) to various intracellular proteins is an essential regulatory step in most eukaryotes. Due to its necessity and the large number of putative targets, SUMO is thought to be second only to ubiquitin (Ub) among Ub-fold proteins in terms of regulatory influence. Whereas, ubiquitylation (i.e., the attachment of Ub) is generally associated with protein...