Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Piezoelectric Plate Sensor (PEPS) for Analysis of Specific KRAS Point Mutations at Low Copy Number in Urine Without DNA Isolation or Amplification.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017

Kirimli Ceyhun E, Shih Wei-Heng, Shih Wan Y

Abstract excerpt

We have examined in situ detection of single-nucleotide KRAS mutations in urine using a (Pb(Mg1/3Nb2/3)O3)0.65(PbTiO3)0.35 (PMN-PT) piezoelectric plate sensor (PEPS) coated with a 17-nucleotide (nt) locked nucleic acid (LNA) probe DNA complementary to the KRAS mutation without DNA isolation and amplification. In situ mutant (MT) DNA in urine in a wild type (WT) background was carried out at a flow rate of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biosensing Techniques
Share to Circulating Tumor DNA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Probes

Share to Gene Dosage

Share to Microscopy, Fluorescence

Share to Point Mutation

Share to Proto-Oncogene Proteins p21(ras)

Share to Sensitivity and Specificity

Source

Identifiers

PMID: 28299698
DOI: 10.1007/978-1-4939-6911-1_22

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Piezoelectric Plate Sensor (PEPS) for Analysis of Specific KRAS Point Mutations at Low Copy Number in Urine Without DNA Isolation or Amplification.PMID 28299698Read ↗

Amplification-free in situ KRAS point mutation detection at 60 copies per mL in urine in a background of 1000-fold wild type.Semantic proximity Read ↗

In situ, amplification-free double-stranded mutation detection at 60 copies/ml with thousand-fold wild type in urine.Semantic proximity Read ↗

Specific in situ hepatitis B viral double mutation (HBVDM) detection in urine with 60 copies ml(-1) analytical sensitivity in a background of 250-fold wild type without DNA isolation and amplification.Semantic proximity Read ↗

Liquid biopsy genotyping by a simple lateral flow strip assay with visual detection.Semantic proximity Read ↗

Direct Detection of Low Abundance Genes of Single Point Mutation.Semantic proximity Read ↗

Exploiting amplification byproducts to enable colorimetric ctDNA detection via nanozyme inhibition.Semantic proximity Read ↗

CRISPR-Cas-amplified urine biomarkers for multiplexed and portable cancer diagnosticsSemantic proximity Read ↗

Clamp the LAMP: a photoelectrochemical platform for KRAS mutation detection via wild-type blocking.Semantic proximity Read ↗

Clamp the LAMP: a photoelectrochemical platform for <i>KRAS</i> mutation detection via wild-type blockingSemantic proximity Read ↗

Multiplex Detection of KRAS Mutations Using Passive Droplet Fusion.Semantic proximity Read ↗

Engineering of a DNA/γPNA Hybrid Nanoreporter for ctDNA Mutation Detection via γPNA Urinalysis.Semantic proximity Read ↗

Acoustic Array Biochip Combined with Allele-Specific PCR for Multiple Cancer Mutation Analysis in Tissue and Liquid Biopsy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.