Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

In situ, amplification-free double-stranded mutation detection at 60 copies/ml with thousand-fold wild type in urine.

Biosensors & bioelectronics - 15 Nov 2018

Kirimli Ceyhun, Lin Selena, Su Ying-Hsiu, Shih Wei-Heng, Shih Wan Y

Abstract excerpt

We have investigated amplification-free in situ double-stranded mutation detection in urine in the concentration range 10-19 M - 10-16 M using piezoelectric plate sensors (PEPs). The detection was carried out in a close-loop flow with two temperature zones. The 95 °C high-temperature zone served as the reservoir where the sample was loaded and DNA de-hybridized. The heated urine was cooled flowing through a 1 m...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biosensing Techniques
Share to DNA, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis B

Share to Hepatitis B virus

Share to Limit of Detection

Share to Mutation

Share to Point Mutation

Share to Urinalysis

Source

Open in PubMed Open full text

Identifiers

PMID: 30142581
DOI: 10.1016/j.bios.2018.07.062
PMCID: PMC6524543

Genes

KRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

In situ, amplification-free double-stranded mutation detection at 60 copies/ml with thousand-fold wild type in urine.PMID 30142581Read ↗

Amplification-free in situ KRAS point mutation detection at 60 copies per mL in urine in a background of 1000-fold wild type.Semantic proximity Read ↗

Piezoelectric Plate Sensor (PEPS) for Analysis of Specific KRAS Point Mutations at Low Copy Number in Urine Without DNA Isolation or Amplification.Semantic proximity Read ↗

Specific in situ hepatitis B viral double mutation (HBVDM) detection in urine with 60 copies ml(-1) analytical sensitivity in a background of 250-fold wild type without DNA isolation and amplification.Semantic proximity Read ↗

CRISPR-Cas-amplified urine biomarkers for multiplexed and portable cancer diagnosticsSemantic proximity Read ↗

Liquid biopsy genotyping by a simple lateral flow strip assay with visual detection.Semantic proximity Read ↗

CRISPR-Cas-amplified urine biomarkers for multiplexed and portable cancer diagnosticsSemantic proximity Read ↗

A universal probe design for colorimetric detection of single-nucleotide variation with visible readout and high specificity.Semantic proximity Read ↗

Label-Free Detection of DNA Mutations by Nanopore Analysis.Semantic proximity Read ↗

PCR free multiple ligase reactions and probe cleavages for the SNP detection of KRAS mutation with attomole sensitivity.Semantic proximity Read ↗

Discrimination of Single-Nucleotide Variants Based on an Allele-Specific Hybridization Chain Reaction and Smartphone Detection.Semantic proximity Read ↗

Double base mismatches mediated catalytic hairpin assembly for enzyme-free single-base mutation detection: integrating signal recognition and amplification in one.Semantic proximity Read ↗

Multiplex Detection of KRAS Mutations Using Passive Droplet Fusion.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.