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Article

The RUNX/CBFβ Complex in Breast Cancer: A Conundrum of Context.

Cells - 16 Feb 2023

Khan Adiba S, Campbell Kirsteen J, Cameron Ewan R, Blyth Karen

Abstract excerpt

Dissecting and identifying the major actors and pathways in the genesis, progression and aggressive advancement of breast cancer is challenging, in part because neoplasms arising in this tissue represent distinct diseases and in part because the tumors themselves evolve. This review attempts to illustrate the complexity of this mutational landscape as it pertains to the RUNX genes and their transcription...

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Identifiers

PMID: 36831308
DOI: 10.3390/cells12040641
PMCID: PMC9953914

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