Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dynamic of contribution of UBPy-sorted cargo to acrosome biogenesis: effects of its derailment in a mouse model of globozoospermia, the infertile Vps54 (L967Q) mutant.

Cell and tissue research - 1 Aug 2017

Gioria Mariarosa, Pasini Maria Enrica, Berruti Giovanna

Abstract excerpt

The sperm acrosome is a specialized vacuole, a member of the family of cell-specific lysosome-related organelles. Its exocytosis, the acrosome reaction, is a crucial event during fertilization. The released acrosomal contents promote sperm penetration through the investments of the oocyte, whereas the membranous components of the acrosome are involved in sperm-oocyte interaction/fusion and oocyte activation. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Endopeptidases
Share to Endosomal Sorting Complexes Required for Transport

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lectins

Share to Proto-Oncogene Proteins c-met

Share to Spermatids

Share to Spermatogenesis

Share to Ubiquitin Thiolesterase

Share to Vesicular Transport Proteins

Source

Identifiers

PMID: 28299521
DOI: 10.1007/s00441-017-2592-1

Genes

EEA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dynamic of contribution of UBPy-sorted cargo to acrosome biogenesis: effects of its derailment in a mouse model of globozoospermia, the infertile Vps54 (L967Q) mutant.PMID 28299521Read ↗

Failure of acrosome formation and globozoospermia in the wobbler mouse, a Vps54 spontaneous recessive mutantSemantic proximity Read ↗

The Acrosomal Matrix.Semantic proximity Read ↗

Human globozoospermia‐related genes and their role in acrosome biogenesisSemantic proximity Read ↗

Loss of the Na+/H+ exchanger NHE8 causes male infertility in mice by disrupting acrosome formationSemantic proximity Read ↗

The molecular mechanisms underlying acrosome biogenesis elucidated by gene-manipulated mice†Semantic proximity Read ↗

Haploid male germ cells—the Grand Central Station of protein transportSemantic proximity Read ↗

Mechanism of Acrosome Biogenesis in MammalsSemantic proximity Read ↗

Lack of acrosome formation in mice lacking a Golgi protein, GOPCSemantic proximity Read ↗

The role of the acrosomal matrix in fertilizationSemantic proximity Read ↗

AU040320 deficiency leads to disruption of acrosome biogenesis and infertility in homozygous mutant mice.Semantic proximity Read ↗

Acrosomal biogenesis in human globozoospermia: immunocytochemical, ultrastructural and proteomic studiesSemantic proximity Read ↗

A Conserved Requirement for Fbxo7 During Male Germ Cell Cytoplasmic RemodelingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.