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Article

Acrosomal biogenesis in human globozoospermia: immunocytochemical, ultrastructural and proteomic studies

17 Apr 2012

Abstract excerpt

BACKGROUND: Acrosome biogenesis is a key event in sperm differentiation that depends on the proper interaction between the Golgi complex and the nuclear envelope of early spermatids. We studied the development, structure and biochemical characteristics of human acrosomes in germ cells and spermatozoa from testicular biopsies and semen samples of fertile men and patients with acrosomeless spermatozoa...

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PMID: 22511613
DOI: 10.1093/humrep/des126

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