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The molecular mechanisms underlying acrosome biogenesis elucidated by gene-manipulated mice†

15 Jun 2021

Abstract excerpt

Sexual reproduction requires the fusion of two gametes in a multistep and multifactorial process termed fertilization. One of the main steps that ensures successful fertilization is acrosome reaction. The acrosome, a special kind of organelle with a cap-like structure that covers the anterior portion of sperm head, plays a key role in the process. Acrosome biogenesis begins with the initial stage of spermatid...

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PMID: 34131698
DOI: 10.1093/biolre/ioab117

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