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Article

Human globozoospermia‐related genes and their role in acrosome biogenesis

9 Dec 2022

Abstract excerpt

The mammalian acrosome is a secretory vesicle attached to the sperm nucleus whose fusion with the overlying plasma membrane is required to achieve fertilization. Acrosome biogenesis starts during meiosis, but it lasts through the entire process of haploid cell differentiation (spermiogenesis). Acrosome biogenesis is a stepwise process that involves membrane traffic from the Golgi apparatus, but it also seems that...

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PMID: 36493758
DOI: 10.1002/wsbm.1589

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