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Article

Failure of acrosome formation and globozoospermia in the wobbler mouse, a Vps54 spontaneous recessive mutant

1 Jan 2011

Abstract excerpt

The acrosome is a unique organelle that plays an important role at fertilization and during sperm morphogenesis and that is absent in globozoospermia, an inherited infertility syndrome in humans. At the light of recent experimental evidence, the acrosome is considered a lysosome-related organelle to whose biogenesis both the endocytic and biosynthetic pathways contribute. Vps54 is a vesicular sorting protein...

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PMID: 21866276
DOI: 10.4161/spmg.1.1.14698

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Failure of acrosome formation and globozoospermia in the wobbler mouse, a Vps54 spontaneous recessive mutantPMID 21866276Read ↗

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