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The enigmatic oncogene and tumor suppressor‐like properties of RAD54B: Insights into genome instability and cancer

14 Mar 2017

Abstract excerpt

One of the major challenges to the cell is to ensure genome stability, which can be compromised through endogenous errors or exogenous DNA damaging agents, such as ionizing radiation or common chemotherapeutic agents. To maintain genome stability the cell has a multifaceted line of defense, including cell cycle checkpoints and DNA damage repair pathways. RAD54B is involved in many of these pathways and thus...

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PMID: 28295846
DOI: 10.1002/gcc.22458

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