Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cerebrospinal fluid mtDNA concentration is elevated in multiple sclerosis disease and responds to treatment

15 Mar 2017

Abstract excerpt

BACKGROUND: Mitochondrial dysfunction is increasingly recognized as an important feature of multiple sclerosis (MS) pathology and may be relevant for clinical disease progression. However, it is unknown whether mitochondrial DNA (mtDNA) levels in the cerebrospinal fluid (CSF) associate with disease progression and therapeutic response. OBJECTIVES: To evaluate whether CSF concentrations of mtDNA in MS patients can...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Neurodegenerative Diseases
Share to Mitochondrial Function and Pathology
Share to Multiple Sclerosis Research Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28294696
DOI: 10.1177/1352458517699874

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cerebrospinal fluid mtDNA concentration is elevated in multiple sclerosis disease and responds to treatmentPMID 28294696Read ↗

The role of mitochondrial DNA variants and dysfunction in the pathogenesis and progression of multiple sclerosis.Semantic proximity Read ↗

Distinct age-related pattern of mitochondrial somatic mutations across multiple sclerosis phenotypes.Semantic proximity Read ↗

Mitochondrial DNA deletions and neurodegeneration in multiple sclerosisSemantic proximity Read ↗

Variations in mitochondrial DNA copy numbers in MS brains.Semantic proximity Read ↗

Cerebrospinal fluid mitochondrial DNA in neuromyelitis optica spectrum disorderSemantic proximity Read ↗

Mitochondrial DNA sequence variation in multiple sclerosis.Semantic proximity Read ↗

Increased levels of cell-free mitochondrial DNA in the cerebrospinal fluid of patients with multiple sclerosisSemantic proximity Read ↗

Cell-free mitochondrial DNA in progressive multiple sclerosisSemantic proximity Read ↗

Next-generation sequencing of the whole mitochondrial genome identifies functionally deleterious mutations in patients with multiple sclerosis.Semantic proximity Read ↗

Cerebrospinal fluid cell-free mitochondrial DNA is associated with HIV replication, iron transport, and mild HIV-associated neurocognitive impairmentSemantic proximity Read ↗

Post-mortem ventricular cerebrospinal fluid cell-free-mtDNA in neurodegenerative diseaseSemantic proximity Read ↗

Increased plasma levels of mitochondrial DNA and pro-inflammatory cytokines in patients with progressive multiple sclerosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.