Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cerebrospinal fluid mitochondrial DNA in neuromyelitis optica spectrum disorder

27 Apr 2018

Abstract excerpt

BACKGROUND: Neuromyelitis optica spectrum disorder (NMOSD) is an inflammatory disease of the central nervous system. Although complement-dependent astrocyte damage mediated by anti-aquaporin 4 autoantibody (AQP4-Ab) is well acknowledged to be the core of NMOSD pathogenesis, additional inflammatory cascades may contribute to the establishment of lesion formation. Thus, in this study, we investigated the possible...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mitochondrial Function and Pathology
Share to Multiple Sclerosis Research Studies
Share to Neuroinflammation and Neurodegeneration Mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29703264
DOI: 10.1186/s12974-018-1162-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cerebrospinal fluid mitochondrial DNA in neuromyelitis optica spectrum disorderPMID 29703264Read ↗

High dimensional mass cytometry analysis unravels distinct profiles of peripheral blood mononuclear cells in patients with neuromyelitis optica spectrum disorder and myelin oligodendrocyte glycoprotein associated disease or in healthSemantic proximity Read ↗

Cell-Free Mitochondrial DNA in the CSF: A Potential Prognostic Biomarker of Anti-NMDAR EncephalitisSemantic proximity Read ↗

Evidence for the Role of Mitochondrial DNA Release in the Inflammatory Response in Neurological Disorders.Semantic proximity Read ↗

mRNA Profiling of Inflammatory Stress Responses after Aquaporin-4 Antibody and Human Complement Treatment Reveals Upregulation of NF-κB and IL6 PathwaysSemantic proximity Read ↗

Cerebrospinal fluid mtDNA concentration is elevated in multiple sclerosis disease and responds to treatmentSemantic proximity Read ↗

Serum Biomarker Profiles Discriminate AQP4 Seropositive and Double Seronegative Neuromyelitis Optica Spectrum DisorderSemantic proximity Read ↗

Next-generation sequencing identifies altered whole blood microRNAs in neuromyelitis optica spectrum disorder which may permit discrimination from multiple sclerosisSemantic proximity Read ↗

Neuromyelitis optica (NMO)--an autoimmune disease of the central nervous system (CNS).Semantic proximity Read ↗

TDP43 augments astrocyte inflammatory activity through mtDNA-cGAS-STING axis in NMOSDSemantic proximity Read ↗

Fluid phase biomarkers in multiple sclerosisSemantic proximity Read ↗

Pro-Inflammatory Molecules Implicated in Multiple Sclerosis Divert the Development of Human Oligodendrocyte Lineage CellsSemantic proximity Read ↗

Epidemiological, clinical and immunological aspects of neuromyelitis optica (NMO).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.