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Article

PTEN proteoforms in biology and disease.

Cellular and molecular life sciences : CMLS - 1 Aug 2017

Malaney Prerna, Uversky Vladimir N, Davé Vrushank

Abstract excerpt

Proteoforms are specific molecular forms of protein products arising from a single gene that possess different structures and different functions. Therefore, a single gene can produce a large repertoire of proteoforms by means of allelic variations (mutations, indels, SNPs), alternative splicing and other pre-translational mechanisms, post-translational modifications (PTMs), conformational dynamics, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28289760
DOI: 10.1007/s00018-017-2500-6
PMCID: PMC11107534

Genes

PTEN

Provenance

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