Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cerebral white matter hyperintensities on MRI and acceleration of epigenetic aging: the atherosclerosis risk in communities study

14 Feb 2017

Abstract excerpt

Cerebral white matter hyperintensities (WMH) on magnetic resonance imaging (MRI) are part of the spectrum of brain vascular injury accompanying aging and are associated with a substantial risk of stroke and dementia. We investigated the association of cerebral WMH burden on MRI with a DNA methylation-based biomarker of aging, termed DNA methylation age acceleration, which represents the deviation of the DNA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dementia and Cognitive Impairment Research
Share to Epigenetics and DNA Methylation
Share to Genetic Associations and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28289478
DOI: 10.1186/s13148-016-0302-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cerebral white matter hyperintensities on MRI and acceleration of epigenetic aging: the atherosclerosis risk in communities studyPMID 28289478Read ↗

Epigenetic Age Acceleration Assessed with Human White-Matter ImagesSemantic proximity Read ↗

DNA methylation age from peripheral blood predicts progression to Alzheimer’s disease, white matter disease burden, and cortical atrophySemantic proximity Read ↗

Peripheral DNA Methylation, Cognitive Decline and Brain Aging: Pilot Findings from The Whitehall II Imaging StudySemantic proximity Read ↗

DNA methylation age from peripheral blood predicts progression to Alzheimer’s disease, white matter disease burden, and cortical atrophySemantic proximity Read ↗

DNA methylation-estimated phenotypes, telomere length and risk of ischemic stroke: epigenetic age acceleration of screening and a Mendelian randomization study.Semantic proximity Read ↗

Epigenetic age acceleration predicts subject‐specific white matter degeneration in the human brainSemantic proximity Read ↗

A blood biomarker of accelerated aging in the body associates with worse structural integrity in the brain: replication across three cohortsSemantic proximity Read ↗

Association of Pace of Aging Measured by Blood-Based DNA Methylation With Age-Related Cognitive Impairment and DementiaSemantic proximity Read ↗

Accelerated Epigenetic Aging Is Associated With Multiple Cardiometabolic, Hematologic, and Renal Abnormalities: A Project Baseline Health SubstudySemantic proximity Read ↗

Aging the Brain: Multi-Region Methylation Principal Component Based Clock in the Context of Alzheimer’s DiseaseSemantic proximity Read ↗

Are sex differences in cognitive impairment reflected in epigenetic age acceleration metrics?Semantic proximity Read ↗

Epigenetic age acceleration and prevalent age- related neurological disorders: a two-sample Mendelian randomization studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.