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Epigenetic Age Acceleration Assessed with Human White-Matter Images

6 Apr 2017

Abstract excerpt

The accurate estimation of age using methylation data has proved a useful and heritable biomarker, with acceleration in epigenetic age predicting a number of age-related phenotypes. Measures of white matter integrity in the brain are also heritable and highly sensitive to both normal and pathological aging processes across adulthood. We consider the phenotypic and genetic interrelationships between epigenetic age...

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PMID: 28385874
DOI: 10.1523/jneurosci.0177-17.2017

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