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Article

Adrenergic Signaling Strengthens Cardiac Myocyte Cohesion.

Circulation research - 14 Apr 2017

Schinner Camilla, Vielmuth Franziska, Rötzer Vera, Hiermaier Matthias, Radeva Mariya Y, Co Thu Kim, Hartlieb Eva, Schmidt Andreas, Imhof Axel, Messoudi Ahmed, Horn Anja, Schlipp Angela, Spindler Volker, Waschke Jens

Abstract excerpt

RATIONALE: The sympathetic nervous system is a major mediator of heart function. Intercalated discs composed of desmosomes, adherens junctions, and gap junctions provide the structural backbone for coordinated contraction of cardiac myocytes. OBJECTIVE: Gap junctions dynamically remodel to adapt to sympathetic signaling. However, it is unknown whether such rapid adaption also occurs for the adhesive function...

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Source

Identifiers

PMID: 28289018
DOI: 10.1161/CIRCRESAHA.116.309631

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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