Article
Identification of endometrial cancer methylation features using combined methylation analysis methods.
PloS one - 1 Jan 2017
Trimarchi Michael P, Yan Pearlly, Groden Joanna, Bundschuh Ralf, Goodfellow Paul J
Abstract excerpt
BACKGROUND: DNA methylation is a stable epigenetic mark that is frequently altered in tumors. DNA methylation features are attractive biomarkers for disease states given the stability of DNA methylation in living cells and in biologic specimens typically available for analysis. Widespread accumulation of methylation in regulatory elements in some cancers (specifically the CpG island methylator phenotype, CIMP)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
