Article
Comparative DNA methylome analysis of endometrial carcinoma reveals complex and distinct deregulation of cancer promoters and enhancers.
BMC genomics - 6 Oct 2014
Zhang Bo, Xing XiaoYun, Li Jing, Lowdon Rebecca F, Zhou Yan, Lin Nan, Zhang Baoxue, Sundaram Vasavi, Chiappinelli Katherine B, Hagemann Ian S, Mutch David G, Goodfellow Paul J, Wang Ting
Abstract excerpt
BACKGROUND: Aberrant DNA methylation is a hallmark of many cancers. Classically there are two types of endometrial cancer, endometrioid adenocarcinoma (EAC), or Type I, and uterine papillary serous carcinoma (UPSC), or Type II. However, the whole genome DNA methylation changes in these two classical types of endometrial cancer is still unknown. RESULTS: Here we described complete genome-wide DNA methylome maps of...
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