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Article

Multifactorial Experimental Design to Optimize the Anti-Inflammatory and Proangiogenic Potential of Mesenchymal Stem Cell Spheroids.

Stem cells (Dayton, Ohio) - 1 Jun 2017

Murphy Kaitlin C, Whitehead Jacklyn, Falahee Patrick C, Zhou Dejie, Simon Scott I, Leach J Kent

Abstract excerpt

Mesenchymal stem cell therapies promote wound healing by manipulating the local environment to enhance the function of host cells. Aggregation of mesenchymal stem cells (MSCs) into three-dimensional spheroids increases cell survival and augments their anti-inflammatory and proangiogenic potential, yet there is no consensus on the preferred conditions for maximizing spheroid function in this application. The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colony-Forming Units Assay

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Source

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Identifiers

PMID: 28276602
DOI: 10.1002/stem.2606
PMCID: PMC5446296

Genes

MSC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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