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Article

HisB as novel selection marker for gene targeting approaches in Aspergillus niger.

BMC microbiology - 8 Mar 2017

Fiedler Markus R M, Gensheimer Tarek, Kubisch Christin, Meyer Vera

Abstract excerpt

BACKGROUND: For Aspergillus niger, a broad set of auxotrophic and dominant resistance markers is available. However, only few offer targeted modification of a gene of interest into or at a genomic locus of choice, which hampers functional genomics studies. We thus aimed to extend the available set by generating a histidine auxotrophic strain with a characterized hisB locus for targeted gene integration and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 28274204
DOI: 10.1186/s12866-017-0960-3
PMCID: PMC5343542

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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