Article
Regulation of the Aspergillus nidulans hisB gene by histidine starvation.
Current genetics - 1 Jan 2001
Busch S, Hoffmann B, Valerius O, Starke K, Düvel K, Braus G H
Abstract excerpt
The hisB gene of the filamentous fungus Aspergillus nidulans encodes imidazole glycerol-phosphate dehydratase (E.C. 4.2.1.19), which catalyses the seventh enzymatic step in histidine biosynthesis. The gene was isolated and its deduced peptide sequence of 247 amino acids showed up to 54% identity with the IGPD enzymes of organisms comprising all three kingdoms. Expression of hisB cDNA in a Saccharomyces cerevisiae...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
