Article
Role of uL3 in Multidrug Resistance in p53-Mutated Lung Cancer Cells.
International journal of molecular sciences - 3 Mar 2017
Russo Annapina, Saide Assunta, Smaldone Silvia, Faraonio Raffaella, Russo Giulia
Abstract excerpt
Cancer is one of the most common causes of death among adults. Chemotherapy is crucial in determining patient survival and quality of life. However, the development of multidrug resistance (MDR) continues to pose a significant challenge in the management of cancer. In this study, we analyzed the role of human ribosomal protein uL3 (formerly rpL3) in multidrug resistance. Our studies revealed that uL3 is a key...
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