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Article

A Predictive Noninvasive Single-Nucleotide Variation-Based Biomarker Signature for Resectable Pancreatic Cancer: Protocol for a Prospective Validation Study.

JMIR research protocols - 13 May 2024

Seeger Nico, Gutknecht Stefan, Zschokke Irin, Fleischmann Isabella, Roth Nadja, Metzger Jürg, Weber Markus, Breitenstein Stefan, Grochola Lukasz Filip

Abstract excerpt

BACKGROUND: Single-nucleotide variations (SNVs; formerly SNPs) are inherited genetic variants that can be easily determined in routine clinical practice using a simple blood or saliva test. SNVs have potential to serve as noninvasive biomarkers for predicting cancer-specific patient outcomes after resection of pancreatic ductal adenocarcinoma (PDAC). Two recent analyses led to the identification and validation of...

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Identifiers

PMID: 38635586
DOI: 10.2196/54042
PMCID: PMC11130767

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