Role for Functional SOD2 Polymorphism in Pulmonary Arterial Hypertension in a Chinese Population.

doi:10.3390/ijerph14030266

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Article

Role for Functional SOD2 Polymorphism in Pulmonary Arterial Hypertension in a Chinese Population.

International journal of environmental research and public health - 6 Mar 2017

Xu Ming, Xu Min, Han Lei, Yuan Chao, Mei Yong, Zhang Hengdong, Chen Shi, Sun Kai, Zhu Baoli

Abstract excerpt

The superoxide dismutase 2 (SOD2) gene is a pivotal part of oxidative stress system, which could induce the onset of pulmonary arterial hypertension (PAH). In this study, we quantified the influence of a SOD2exonic polymorphism (rs4880) on PAH susceptibility. We genotyped this single nucleotide polymorphism (SNP) by TaqMan, and evaluated its association with PAH susceptibility in a case-control study of 460...

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Identifiers

PMID: 28272301
DOI: 10.3390/ijerph14030266
PMCID: PMC5369102

Genes

PAH
SOD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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