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Article

Epigenetic modulation as a therapeutic approach for pulmonary arterial hypertension

1 Jul 2015

Abstract excerpt

Pulmonary arterial hypertension (PAH) is a rare but progressive and currently incurable disease, which is characterized by vascular remodeling in association with muscularization of the arterioles, medial thickening and plexiform lesion formation. Despite our advanced understanding of the pathogenesis of PAH and the recent therapeutic advances, PAH still remains a fatal disease. In addition, the susceptibility to...

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PMID: 26228095
DOI: 10.1038/emm.2015.45

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