Article
VEGF Promoter Polymorphism Confers an Increased Risk of Pulmonary Arterial Hypertension in a Chinese Population.
Yonsei medical journal - 1 Mar 2017
Zhuo Yufeng, Zeng Qingchun, Zhang Peng, Li Guoyang, Xie Qiang, Cheng Ying
Abstract excerpt
PURPOSE: Evidence on the contribution of genes to the hereditary predisposition to pulmonary arterial hypertension (PAH) is limited. MATERIALS AND METHODS: In this study, we hypothesized that single nucleotide variants in vascular endothelial growth factor (VEGF) gene may alter gene function and expression and may be associated with PAH risk. Five putatively functional loci (rs699947C>A and rs833061T>C in the...
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