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Association between genetic polymorphism of telomere-associated gene ACYP2 and the risk of HAPE among the Chinese Han population: A Case-control study.

Medicine - 1 Mar 2017

Zhu Linhao, Liu Lijun, He Xue, Yan Mengdan, Du Jieli, Yang Hua, Zhang Yuan, Yuan Dongya, Jin Tianbo

Abstract excerpt

High-altitude pulmonary edema (HAPE) is a hypoxia-induced, life-threatening, pulmonary edema, which is characterized by exaggerated pulmonary hypertension caused by stress failure. ACYP2 was found to associated with telomere length, the aim of this study was to identify whether ACYP2 polymorphisms increase or decrease HAPE risk in the Chinese Han individuals.In present study, we have genotyped 7 single-nucleotide...

Topics

Acid Anhydride Hydrolases
Adult
Altitude Sickness
Asian People
Case-Control Studies
China
Female
Humans
Hypertension, Pulmonary
Male
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Telomere Homeostasis

Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 28353602
DOI: 10.1097/MD.0000000000006504
PMCID: PMC5380286

Genes

ACYP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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