Article
Relation between endothelial nitric oxide synthase genetic polymorphisms and pulmonary arterial hypertension in newborns with congenital heart disease.
Clinical and experimental hypertension (New York, N.Y. : 1993) - 18 Aug 2022
Lin Qing-Fan, Rao Jing-Hong, Luo Shi-Mu, Wang Qing-Mu, Deng Li-Feng, Chen Xuan, Chen Chang-Di, Chen You-Fang
Abstract excerpt
OBJECTIVE: To investigate whether endothelial nitric oxide synthase (eNOS) rs1799983, rs2070744, and rs61722009 gene polymorphisms are associated with pulmonary arterial hypertension (PAH) in South Fujian newborns with congenital heart disease (CHD). METHODS: Genotyping for the eNOS rs1799983, rs2070744, and polymorphisms was performed using Sanger sequencing in 50 newborns with PAH secondary to CHD...